You will help develop a humanized Joint-on-Chip (JoC) platform for in vitro modeling of OA-related inflammatory phenotypes.
Job descriptionThe position is part of the NWO-Perspectief programma OAinject. This national research consortium aims to develop diagnostic tools for early assessment of osteoarthritis (OA) and patient stratification, in combination with easy-to-use disease phenotype-specific intra-articular injection therapies. You will be involved in the development of a humanized Joint-on-Chip (JoC) platform for in vitro modeling of different pathological - OA-relevant - inflammatory phenotypes. The technical part of the development of this platform will be done by a researcher at the University of Twente. For this position, the focus will be on modeling and understanding various causes of inflammation using different types of primary human cells in culture.
Work environmentYou will be appointed at the department of Orthopaedics and Sports Medicine in the Connective Tissue Repair laboratory. The laboratory hosts a multidisciplinary group of approximately 15 persons including academic staff, PhD students, postdocs and technicians. You are going to work together with experts in cartilage biology, in vitro models, inflammation, genetics and mechanical loading at Erasmus MC and University of Twente. You will be supervised by dr. Roberto Narcisi and prof.dr. Gerjo van Osch.
Qualifications and skillsFor this position experience with cell or tissue culture, immuno-fluorescence and with basic (molecular) biology methods and techniques (e.g. Realtime-PCR, immuno-histochemistry) is required. Knowledge and experience in inflammation, musculo-skeletal tissues/cells or organ-on-chip models is a plus. You are creative and you are keen to work in an interdisciplinary team. It is important that you are able to work both independently and within a team. You also have:
- A strong scientific interest and affinity for research in the field of inflammation, cartilage (molecular) biology and disease modeling, with an interest in working with organ-on-Chip model.
- Genuine interest in fundamental research.
- A relevant master, for example in biomedical science, biotechnology, biomedical engineering. We will also consider candidates with a PhD.
- A good command (oral and written) of English.
- A high level of motivation and commitment to produce high-quality work and good organizational and excellent analytical skills.
Based on your application, we check to see if there is a fit between us. We will let you know as soon as possible whether you are invited for an interview.
Step 3 - Job interviewYou have been invited for an interview, great! In this first meeting we get to know each other and see if you can form an idea of the position, the department and Erasmus MC. If the interview goes well usually a second interview follows.
Step 4 - Offer and terms of employmentIt's a match! Your future manager will discuss your salary and employment with you. You will also receive more information about our other terms of employment.
Step 5 - Getting startedYour first working day has come! We are more than happy to have you. Your new department will give you a warm welcome and provide you with all the information you need. Enjoy your job at Erasmus MC!
Het salaris bedraagt €3017 - €3824